The Hidden Link Between Factory Farms and Human Illness

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In fact, public health experts are beginning to suspect that a whole host of infections not previously thought of as food-related may ultimately be linked to the overuse of antibiotics in animal agriculture. Researchers at the University of California-Berkeley, for example, traced a multi-state outbreak of urinary tract infections among women in 1999 and 2000 to contamination with a single strain of drug-resistant E. coli found in cows. Dr. Lee Riley, lead author of a paper on the findings published in Clinical Infectious Diseases, cautioned that the findings indicated that “the problem of foodborne disease is much greater in scope than we had ever previously thought.”

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And then there’s methicillin-resistant Staphylococcus aureus, or MRSA. Previously confined largely to hospitals, MRSA is now killing more people in the United States each year than HIV/AIDS. A series of recent studies in Europe have demonstrated a strong causal link between MRSA and intensive pig farming in the Netherlands, Germany and France. Little or no data are available on MRSA in animals in the United States, but the bacterium is widely present on pig farms in Canada, which sells millions of live pigs to the United States annually, so it seems pretty likely it’s in U.S. pig factories, too.

All in all, the CDC reports that 2 million people in the United States now contract an infection each year while in the hospital. Of those, a staggering 90,000 die — a toll higher than that from diabetes. Numbers such as that are prompting some medical investigators to suggest that we may be entering a “post-antibiotic era,” one in which (as a paper published in Environmental Health Perspectives in 2007 put it) “there would be no effective antibiotics available for treating many life-threatening infections in humans.”

Connections such as these aren’t always easy to prove, however, especially for drugs that have already been in widespread use for decades, which is one reason why regulations to reign in the non-therapeutic use of antimicrobials have so far been largely lacking in the United States. The pending approval of an antibiotic called cefquinome to treat respiratory diseases in cattle offered a recent test case. Cefquinome is similar to cefepime, a last-resort antibiotic used to treat serious infections in people. (Both are fourth-generation cephalosporins, one of the small number of new antibiotics developed in recent years.) The FDA’s Veterinary Medicine Advisory Committee, along with the Centers for Disease Control and Prevention and the American Medical Association, recommended against approval, warning that using cefquinome for animals would almost certainly render cefepime less effective for humans. But the FDA has apparently caved to industry pressure, claiming it lacks the authority to deny the drug companies’ request.

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