Natural Relief from Headaches, Even Migraines
(Page 5 of 6)
April/May 2007
By Linda B. White, M.D.
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Feverfew (Tanacetum parthenium) looks like a tiny daisy and, in fact, comes from the same tribe of plants (Asteraceae). Active ingredients, such as parthenolide, reduce pain and inflammation, decrease platelet adhesion, and prevent mast cells from releasing histamine, which causes blood vessels to dilate and leak fluids.
Out of eight studies on feverfew’s ability to prevent migraines, most found some degree of benefit. A 2004 analysis of five studies judged feverfew’s effectiveness unconvincing. However, in a recent, well-designed clinical trial, 170 German patients took a placebo pill or an extract of feverfew for 16 weeks. Those taking feverfew had significantly fewer migraines.
Feverfew is usually taken daily to prevent, rather than treat, migraines. If you do take feverfew long-term, know that there have been some reports of rebound headaches upon discontinuing the herb. Herbal experts often recommend tapering off the dose.
Butterbur (Petasites hybridus) also is a member of the Asteraceae family. Traditionally used to treat spasms in the respiratory and digestive tract, the leaves and rhizomes contain petasin, which relaxes smooth muscle tissue and also inhibits the formation of inflammatory substances called leukotrienes. The plant also contains liver toxins called pyrrolizidine alkaloids (PAs), so it’s important to choose a formula that’s PA-free. Three clinical trials (including one in children and teens) have shown that this herb, taken preventively, safely and effectively reduces the number of migraines. Benefits become obvious at about four weeks.
Drugs and Precautions
Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) — aspirin, naproxen (Aleve) and ibuprofen (Advil, Motrin) — reduce pain and inflammation, and can head off mild headaches. But when the recommended dose is exceeded, they carry a risk of gastrointestinal bleeding. And acetaminophen, the active ingredient in Tylenol, can cause serious liver damage when misused. In fact, the U.S. Federal Drug Administration proposed new labeling rules to make consumers more aware of the dangers associated with these drugs.
Another group of drugs called “triptans” can nip migraine pain in the bud. This class of drugs includes sumatriptan (Imitrex), rizatriptan (Maxalt) and zolmitriptan (Zomig). Unfortunately, people with uncontrolled high blood pressure and heart disease can’t take triptans because they can constrict not only the cerebral (brain) arteries, but also the coronary (heart) arteries.
Paradoxically, the very drugs that bring headache relief can, with repeated use, give rise to chronic daily headaches. Though the cause of this phenomenon remains uncertain, researchers think continued overuse of analgesics may sensitize central pain pathways. And it doesn’t take much medication to develop an overuse problem. Just three months of taking simple analgesics (Advil, Motrin, etc.) for 15 days a month can trigger daily headaches; as can stronger medications such as triptans, opioids or combination analgesics (Fiorinal, Fioricet) taken just 10 days a month. The cure involves stopping these medications, which sounds simple until you factor in the rebound headache, which can last four days. Talk to your doctor about strategies for slowly tapering off medications and reducing pain during the transition.
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