THE HEALTH EFFECTS OF MARIJUANA

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TWO OFFICIAL PERSPECTIVES

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Two organizations have attempted to make sense of the conflicting data: NIDA (a division of the U.S. Department of Health and Human Services) and its Canadian counterpart, the Addiction Research Foundation (a branch of the Ontario Ministry of Health). Neither of the organizations can be considered a completely disinterested observer . . . since their funding comes from legislative bodies which have kept marijuana illegal. But despite possible bias, the reports are fairly consistent with each other and provide reasonable overviews of the current "official" consensus on the adverse effects of this drug. Here are the agencies' conclusions:

[1] Smoking pot irritates the throat and lungs and may cause bronchitis in heavy users.

[2] Careful comparison of smoke condensates shows that one joint deposits about 50% more "tar" in the lungs than does one nonfiltered cigarette, largely because joints tend to be smoked down to smaller butts, and pot smokers typically hold the smoke in their lungs longer.

[3] Marijuana's smoke has as many carcinogenic polycylic aromatic hydrocarbons (PAH's) as tobacco smoke does, although some PAH's—benzopyrene, for example—are more abundant in pot smoke, while others are less. Marijuana, however, contains neither nicotine—which is a very potent poison—nor (in most cases) the pesticide residues typically found in tobacco smoke, which may accelerate the tumor-inducing effects of PAH's.

[4] The use of marijuana increases the heart rate and may prove hazardous to those with heart diseases. It also reduces testosterone levels in men to the lower end of the normal scale . . . though these levels do rise again after the cessation of smoking. The drug also appears to reduce both sperm count and sperm motility. The active ingredient in marijuana, delta-9-tetrahydrocannabinol (THC), apparently stimulates these changes, because it binds to estrogen (the female hormone) receptors and exerts "a weak, but significant" estrogenic effect. (This activity may be the reason why there've been anecdotal reports of breast development, gynecomastia, in men who were heavy users.)

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